SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2llz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 4 LEU A  52
ILE A  72
ARG A  73
TYR A  34
 None
 1.26A 1rk3A-2llzA:
undetectable		 1rk3A-2llzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 6 ASP A  92
GLU A  45
TYR A  46
ARG A  50
 None
 1.45A 1yc2A-2llzA:
undetectable
1yc2B-2llzA:
undetectable
1yc2E-2llzA:
undetectable		 1yc2A-2llzA:
14.45
1yc2B-2llzA:
14.45
1yc2E-2llzA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 7 LEU A  52
ILE A  72
ARG A  73
TYR A  34
 None
 1.24A 2hc4A-2llzA:
undetectable		 2hc4A-2llzA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 7 LEU A  52
VAL A  13
THR A  11
ASP A  44
 None
 1.03A 2zaxA-2llzA:
undetectable		 2zaxA-2llzA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 5 LEU A  52
ILE A  72
ARG A  73
TYR A  34
 None
 1.27A 2zlcA-2llzA:
undetectable		 2zlcA-2llzA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 7 LEU A  52
VAL A  13
THR A  11
ASP A  44
 None
 1.05A 3fwgB-2llzA:
undetectable		 3fwgB-2llzA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		3 / 3 TYR A  34
ARG A  30
SER A  31
 None
 0.76A 4dr2I-2llzA:
undetectable
4dr2J-2llzA:
2.8		 4dr2I-2llzA:
23.31
4dr2J-2llzA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		4 / 7 ASN A  55
PHE A  16
ASN A  87
ASP A  85
 None
 1.43A 4kcnB-2llzA:
undetectable		 4kcnB-2llzA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		3 / 3 TYR A  34
ARG A  30
SER A  31
 None
 0.85A 4lf7I-2llzA:
undetectable
4lf7J-2llzA:
3.0		 4lf7I-2llzA:
23.31
4lf7J-2llzA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2llz UNCHARACTERIZED
PROTEIN YJDK
(Escherichia
coli) 		3 / 3 TYR A  34
ARG A  30
SER A  31
 None
 0.85A 4lf8I-2llzA:
undetectable
4lf8J-2llzA:
3.0		 4lf8I-2llzA:
23.31
4lf8J-2llzA:
23.48