SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lm3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J5M_A_ACTA1321_0 (CHLOROPEROXIDASE)	2lm3	TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (Macaca mulatta)	4 / 6	ASN A 308 ILE A 315 VAL A 322 ALA A 313	None	0.99A	2j5mA-2lm3A: undetectable	2j5mA-2lm3A: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_D_ZPCD1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2lm3	TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (Macaca mulatta)	4 / 7	GLU A 395 GLU A 392 TYR A 480 VAL A 453	None	1.03A	4a97D-2lm3A: undetectable	4a97D-2lm3A: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUD_A_SAMA303_0 (CATECHOL O-METHYLTRANSFERASE)	2lm3	TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (Macaca mulatta)	5 / 12	VAL A 352 GLY A 378 ILE A 406 GLN A 418 TRP A 404	None	1.45A	4xudA-2lm3A: undetectable	4xudA-2lm3A: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YMG_A_SAMA1001_0 (PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE)	2lm3	TRIPARTITE MOTIF-CONTAINING PROTEIN 5 (Macaca mulatta)	5 / 12	GLY A 378 TYR A 364 GLU A 392 ASN A 482 TYR A 397	None	1.49A	4ymgA-2lm3A: undetectable	4ymgA-2lm3A: 20.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2J5M_A_ACTA1321_0","CHLOROPEROXIDASE","2lm3","TRIPARTITE MOTIF-CONTAINING PROTEIN 5","Macaca mulatta",4,"ASN A 308;ILE A 315;VAL A 322;ALA A 313","None","0.99A","2j5mA-2lm3A:undetectable","2j5mA-2lm3A:20.79"],["4A97_D_ZPCD1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","2lm3","TRIPARTITE MOTIF-CONTAINING PROTEIN 5","Macaca mulatta",4,"GLU A 395;GLU A 392;TYR A 480;VAL A 453","None","1.03A","4a97D-2lm3A:undetectable","4a97D-2lm3A:20.83"],["4XUD_A_SAMA303_0","CATECHOL O-METHYLTRANSFERASE","2lm3","TRIPARTITE MOTIF-CONTAINING PROTEIN 5","Macaca mulatta",5,"VAL A 352;GLY A 378;ILE A 406;GLN A 418;TRP A 404","None","1.45A","4xudA-2lm3A:undetectable","4xudA-2lm3A:21.29"],["4YMG_A_SAMA1001_0","PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE","2lm3","TRIPARTITE MOTIF-CONTAINING PROTEIN 5","Macaca mulatta",5,"GLY A 378;TYR A 364;GLU A 392;ASN A 482;TYR A 397","None","1.49A","4ymgA-2lm3A:undetectable","4ymgA-2lm3A:20.33"]]