SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lm4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2lm4 SUCCINATE
DEHYDROGENASE
ASSEMBLY FACTOR 2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  64
TYR A  73
LEU A  42
TYR A  61
GLU A  67
 None
 1.28A 3bgrA-2lm4A:
undetectable
3bgrB-2lm4A:
undetectable		 3bgrA-2lm4A:
12.32
3bgrB-2lm4A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 2lm4 SUCCINATE
DEHYDROGENASE
ASSEMBLY FACTOR 2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  61
GLY A  44
SER A  43
LEU A  42
 None
 1.11A 5bphB-2lm4A:
undetectable		 5bphB-2lm4A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2lm4 SUCCINATE
DEHYDROGENASE
ASSEMBLY FACTOR 2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  61
GLY A  44
SER A  43
LEU A  42
 None
 1.13A 5bphD-2lm4A:
undetectable		 5bphD-2lm4A:
13.96