SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lm5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A 153
PHE A 115
PHE A 173
GLY A 166
 None
 0.89A 3em0B-2lm5A:
undetectable		 3em0B-2lm5A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A 173
ILE A 168
VAL A 176
ILE A 156
LEU A 131
 None
 1.15A 3fpjB-2lm5A:
undetectable		 3fpjB-2lm5A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 145
LEU A 144
ILE A 153
SER A 147
LYS A 150
 None
 1.44A 3h6tA-2lm5A:
undetectable
3h6tC-2lm5A:
undetectable		 3h6tA-2lm5A:
21.13
3h6tC-2lm5A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ARG A 143
LEU A 152
GLU A 148
 None
 0.68A 4l3gF-2lm5A:
undetectable		 4l3gF-2lm5A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 190
ALA A 111
PHE A  98
 None
 0.87A 4olbA-2lm5A:
undetectable		 4olbA-2lm5A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 190
ALA A 111
PHE A  98
 None
 0.84A 4z4iA-2lm5A:
undetectable		 4z4iA-2lm5A:
12.41