SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 8 ILE A 100
LEU A 105
MET A 124
GLU A 127
ALA A 128
 None
 1.05A 1a29A-2lmvA:
10.3		 1a29A-2lmvA:
66.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 9 ILE A 100
LEU A 105
MET A 124
GLU A 127
ALA A 128
 None
 0.88A 1ctrA-2lmvA:
10.1		 1ctrA-2lmvA:
66.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 11 ILE A 100
LEU A 105
MET A 109
LEU A 112
MET A 124
 None
 0.89A 1dtlA-2lmvA:
8.5		 1dtlA-2lmvA:
38.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 12 ALA A  88
ILE A  91
PHE A  92
PHE A 141
LEU A   4
 None
 0.87A 1dtlA-2lmvA:
8.5		 1dtlA-2lmvA:
38.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA156_1
(CALMODULIN)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 8 ILE A 100
LEU A 105
ILE A 125
GLU A 127
ILE A 136
 None
 0.60A 1linA-2lmvA:
10.6		 1linA-2lmvA:
66.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA156_1
(CALMODULIN)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 8 ILE A 100
LEU A 105
MET A 124
ILE A 125
GLU A 127
 None
 1.00A 1linA-2lmvA:
10.6		 1linA-2lmvA:
66.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		6 / 12 LEU A 105
MET A 109
LEU A 112
MET A 124
ILE A 125
GLU A 127
 None
 1.06A 1lxfC-2lmvA:
8.4		 1lxfC-2lmvA:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 10 MET A 109
LEU A 112
GLU A 120
MET A 124
MET A 144
 None
 1.02A 1wrkA-2lmvA:
10.4
1wrkB-2lmvA:
10.7		 1wrkA-2lmvA:
27.67
1wrkB-2lmvA:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 10 MET A 109
LEU A 112
GLU A 120
MET A 124
MET A 144
 None
 1.10A 1wrlC-2lmvA:
10.2
1wrlD-2lmvA:
10.3		 1wrlC-2lmvA:
27.67
1wrlD-2lmvA:
27.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		4 / 7 ARG A 126
ILE A 136
ASN A 137
GLU A 140
 None
None
CA  A 150 ( 4.7A)
CA  A 150 (-2.2A)
 1.07A 4g0vA-2lmvA:
undetectable		 4g0vA-2lmvA:
11.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 8 PHE A  92
ILE A 100
LEU A 105
MET A 109
MET A 124
 None
 0.96A 4rjdA-2lmvA:
3.0		 4rjdA-2lmvA:
72.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2lmv CALMODULIN-RELATED
PROTEIN 97A
(Drosophila
melanogaster) 		5 / 7 PHE A  92
LEU A 105
MET A 109
MET A 124
ALA A 128
 None
 1.09A 4rjdB-2lmvA:
10.8		 4rjdB-2lmvA:
72.73