SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ln7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 GLU A 138
LYS A  97
TRP A  99
GLU A  78
 None
 1.41A 4a7tA-2ln7A:
0.0		 4a7tA-2ln7A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 GLU A 138
LYS A  97
TRP A  99
GLU A  78
 None
 1.45A 4a7tF-2ln7A:
undetectable		 4a7tF-2ln7A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 GLU A 138
LYS A  97
TRP A  99
GLU A  78
 None
 1.38A 4a7uA-2ln7A:
0.0		 4a7uA-2ln7A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 6 ILE A  30
GLY A  44
ILE A 109
LEU A  84
 None
 0.78A 4o8fB-2ln7A:
undetectable		 4o8fB-2ln7A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ARG A 134
ILE A 100
PRO A 132
ASP A 130
 None
 1.08A 4w5oA-2ln7A:
undetectable		 4w5oA-2ln7A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ARG A 134
ILE A 100
PRO A 132
ASP A 130
 None
 1.08A 4z4eA-2ln7A:
undetectable		 4z4eA-2ln7A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ARG A 134
ILE A 100
PRO A 132
ASP A 130
 None
 1.04A 4z4gA-2ln7A:
undetectable		 4z4gA-2ln7A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 2ln7 LPXTG-SITE
TRANSPEPTIDASE
FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 9 LEU A 141
VAL A  83
LEU A  84
ILE A  21
ASP A  80
 None
 1.48A 5tixA-2ln7A:
undetectable		 5tixA-2ln7A:
22.45