SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 5 ASP A  85
LEU A  54
ALA A  84
LEU A 116
 None
 1.10A 1nh8A-2lnlA:
undetectable		 1nh8A-2lnlA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 4 LEU A 262
GLY A 284
ASP A 288
TYR A 258
 None
 1.41A 1oxrA-2lnlA:
undetectable		 1oxrA-2lnlA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 6 LEU A  37
VAL A 261
VAL A 272
ILE A 283
 None
 0.74A 2hyyB-2lnlA:
undetectable		 2hyyB-2lnlA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 6 LEU A  37
VAL A 261
VAL A 272
ILE A 283
 None
 0.77A 3k5vA-2lnlA:
undetectable		 3k5vA-2lnlA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 7 LEU A  65
SER A 298
LEU A  81
SER A  53
 None
 0.96A 3r9vA-2lnlA:
2.1
3r9vB-2lnlA:
1.7		 3r9vA-2lnlA:
23.10
3r9vB-2lnlA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 8 HIS A 179
VAL A 113
GLN A 176
ARG A 279
 None
 1.18A 3uy4A-2lnlA:
undetectable		 3uy4A-2lnlA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 5 LEU A 202
PHE A 171
ARG A 175
PRO A 170
 None
 0.96A 3vm4A-2lnlA:
undetectable		 3vm4A-2lnlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		3 / 3 ARG A 175
THR A 195
TRP A 198
 None
 0.91A 4d7hA-2lnlA:
undetectable		 4d7hA-2lnlA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		3 / 3 ARG A 175
THR A 195
TRP A 198
 None
 1.05A 4ug5A-2lnlA:
undetectable		 4ug5A-2lnlA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		3 / 3 ARG A 175
THR A 195
TRP A 198
 None
 0.92A 4uglA-2lnlA:
undetectable		 4uglA-2lnlA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		3 / 3 ARG A 175
THR A 195
TRP A 198
 None
 0.97A 5g6cA-2lnlA:
undetectable		 5g6cA-2lnlA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1
(Homo
sapiens) 		4 / 7 GLN A 176
ILE A 283
GLN A 271
TYR A 258
 None
 0.87A 5vlmC-2lnlA:
undetectable		 5vlmC-2lnlA:
23.34