SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)
2lnu UNCHARACTERIZED
PROTEIN

(Haloarcula
marismortui)
5 / 11 HIS A  60
HIS A  80
LEU A 108
LEU A  84
THR A  83
None
1.29A 1dmyA-2lnuA:
undetectable
1dmyA-2lnuA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)
2lnu UNCHARACTERIZED
PROTEIN

(Haloarcula
marismortui)
4 / 6 ARG A  52
ASP A 145
THR A 143
ASP A   4
None
1.15A 2j2pE-2lnuA:
undetectable
2j2pF-2lnuA:
undetectable
2j2pE-2lnuA:
20.18
2j2pF-2lnuA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)
2lnu UNCHARACTERIZED
PROTEIN

(Haloarcula
marismortui)
5 / 12 LEU A 130
PHE A  86
PRO A 111
ASN A 169
LEU A 171
None
1.15A 2w3bB-2lnuA:
undetectable
2w3bB-2lnuA:
22.38