SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lnv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		4 / 7 LEU A  95
SER A  96
ASP A 161
PHE A 120
 None
 1.15A 1ismB-2lnvA:
undetectable		 1ismB-2lnvA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		4 / 5 LEU A 145
PRO A 129
VAL A 128
ILE A 135
 None
 0.90A 2aoiB-2lnvA:
undetectable		 2aoiB-2lnvA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		4 / 7 LEU A 145
GLY A  99
PRO A 129
ILE A 135
 None
 0.79A 2aojB-2lnvA:
undetectable		 2aojB-2lnvA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 9 LEU A 145
ILE A 110
PRO A 129
VAL A 128
ILE A 135
 None
 0.97A 2avoA-2lnvA:
undetectable		 2avoA-2lnvA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 9 LEU A 145
ILE A 110
PRO A 129
VAL A 128
ILE A 135
 None
 1.03A 2r5qC-2lnvA:
undetectable		 2r5qC-2lnvA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		4 / 7 ASN A  94
LEU A  95
TYR A 147
VAL A 128
 None
 1.11A 2uz2A-2lnvA:
undetectable		 2uz2A-2lnvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 9 LEU A 145
ILE A 110
GLY A  99
PRO A 129
ILE A 135
 None
 1.08A 3ekqB-2lnvA:
undetectable		 3ekqB-2lnvA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 12 LEU A 145
GLY A  99
PRO A 129
VAL A 128
ILE A 135
 None
 0.90A 4dqbA-2lnvA:
undetectable		 4dqbA-2lnvA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 12 SER A 109
ILE A 138
LEU A  97
GLY A  99
TYR A 157
 None
 1.24A 4foxD-2lnvA:
undetectable		 4foxD-2lnvA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 12 SER A 109
ILE A 138
LEU A  97
GLY A  99
TYR A 157
 None
 1.30A 4foxE-2lnvA:
undetectable		 4foxE-2lnvA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 9 LEU A 145
ILE A 110
GLY A  99
PRO A 129
ILE A 135
 None
 1.13A 5kr2D-2lnvA:
undetectable		 5kr2D-2lnvA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 2lnv GENERAL SECRETION
PATHWAY PROTEIN C
(Dickeya
dadantii) 		5 / 9 LEU A 145
ILE A 110
PRO A 129
VAL A 128
ILE A 135
 None
 1.00A 5kr2D-2lnvA:
undetectable		 5kr2D-2lnvA:
17.43