SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2lop TRANSMEMBRANE
PROTEIN 14A
(Homo
sapiens) 		4 / 6 ILE A  77
PRO A  79
PHE A  71
ARG A  73
 None
 1.37A 1oniA-2lopA:
undetectable
1oniC-2lopA:
undetectable		 1oniA-2lopA:
25.69
1oniC-2lopA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 2lop TRANSMEMBRANE
PROTEIN 14A
(Homo
sapiens) 		5 / 12 MET A  89
LEU A  92
LEU A  96
GLY A  36
LEU A  33
 None
 1.09A 2j7xA-2lopA:
undetectable		 2j7xA-2lopA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2lop TRANSMEMBRANE
PROTEIN 14A
(Homo
sapiens) 		5 / 12 LEU A  88
MET A  89
LEU A  92
GLY A  32
LEU A  29
 None
 0.99A 4xi3C-2lopA:
undetectable		 4xi3C-2lopA:
17.37