SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lpb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FJ1_A_CTCA222_0 (TETRACYCLINE REPRESSOR PROTEIN CLASS D)	2lpb	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 (Saccharomyces cerevisiae)	5 / 12	PRO A 191 THR A 200 VAL A 199 LEU A 183 ILE A 186	None	1.46A	2fj1A-2lpbA: undetectable	2fj1A-2lpbA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_A_20JA602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2lpb	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 (Saccharomyces cerevisiae)	4 / 7	TYR A 220 VAL A 199 ILE A 186 ARG A 185	None	0.68A	4lv9A-2lpbA: undetectable	4lv9A-2lpbA: 8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	2lpb	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 (Saccharomyces cerevisiae)	4 / 7	TYR A 220 VAL A 199 ILE A 186 ARG A 185	None	0.71A	4lv9B-2lpbA: undetectable	4lv9B-2lpbA: 8.57