SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HCJ_B_TACB888_1 (PROTEIN CHAIN ELONGATION FACTOR EF-TU)	2lpd	UNCHARACTERIZED PROTEIN (Burkholderia pseudomallei)	4 / 4	THR A 58 SER A 21 ASP A 23 PRO A 19	None	1.39A	2hcjA-2lpdA: 0.0 2hcjB-2lpdA: 0.0	2hcjA-2lpdA: 15.79 2hcjB-2lpdA: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_B_TACB1888_1 (ELONGATION FACTOR EF-TU)	2lpd	UNCHARACTERIZED PROTEIN (Burkholderia pseudomallei)	4 / 5	THR A 58 SER A 21 ASP A 23 PRO A 19	None	1.47A	2hdnA-2lpdA: undetectable 2hdnB-2lpdA: undetectable 2hdnD-2lpdA: undetectable	2hdnA-2lpdA: 15.79 2hdnB-2lpdA: 16.30 2hdnD-2lpdA: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_D_TACD2888_1 (ELONGATION FACTOR EF-TU)	2lpd	UNCHARACTERIZED PROTEIN (Burkholderia pseudomallei)	4 / 5	THR A 58 SER A 21 ASP A 23 PRO A 19	None	1.47A	2hdnB-2lpdA: undetectable 2hdnC-2lpdA: undetectable 2hdnD-2lpdA: undetectable	2hdnB-2lpdA: 16.30 2hdnC-2lpdA: 15.79 2hdnD-2lpdA: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	2lpd	UNCHARACTERIZED PROTEIN (Burkholderia pseudomallei)	3 / 3	THR A 11 MET A 9 HIS A 8	None	0.72A	5uunA-2lpdA: undetectable	5uunA-2lpdA: 14.09

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HCJ_B_TACB888_1","PROTEIN CHAIN ELONGATION FACTOR EF-TU;PROTEIN CHAIN ELONGATION FACTOR EF-TU","2lpd","UNCHARACTERIZED PROTEIN","Burkholderia pseudomallei",4,"THR A  58;SER A  21;ASP A  23;PRO A  19","None","1.39A","2hcjA-2lpdA:0.0;2hcjB-2lpdA:0.0","2hcjA-2lpdA:15.79;2hcjB-2lpdA:16.30"],["2HDN_B_TACB1888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","2lpd","UNCHARACTERIZED PROTEIN","Burkholderia pseudomallei",4,"THR A  58;SER A  21;ASP A  23;PRO A  19","None","1.47A","2hdnA-2lpdA:undetectable;2hdnB-2lpdA:undetectable;2hdnD-2lpdA:undetectable","2hdnA-2lpdA:15.79;2hdnB-2lpdA:16.30;2hdnD-2lpdA:16.30"],["2HDN_D_TACD2888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","2lpd","UNCHARACTERIZED PROTEIN","Burkholderia pseudomallei",4,"THR A  58;SER A  21;ASP A  23;PRO A  19","None","1.47A","2hdnB-2lpdA:undetectable;2hdnC-2lpdA:undetectable;2hdnD-2lpdA:undetectable","2hdnB-2lpdA:16.30;2hdnC-2lpdA:15.79;2hdnD-2lpdA:16.30"],["5UUN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","2lpd","UNCHARACTERIZED PROTEIN","Burkholderia pseudomallei",3,"THR A  11;MET A   9;HIS A   8","None","0.72A","5uunA-2lpdA:undetectable","5uunA-2lpdA:14.09"]]