SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lpe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2lpe KINASE SUPPRESSOR OF
RAS 1
(Mus
musculus) 		3 / 3 THR A 169
ASP A  25
SER A  95
 None
 0.85A 2nxeB-2lpeA:
undetectable		 2nxeB-2lpeA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2lpe KINASE SUPPRESSOR OF
RAS 1
(Mus
musculus) 		4 / 8 LEU A 133
VAL A 121
VAL A 116
LEU A 128
 None
 1.05A 4q0bA-2lpeA:
undetectable		 4q0bA-2lpeA:
14.03