SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lpu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		3 / 3 ALA A 120
VAL A 122
TRP A 133
 None
 0.91A 1av2A-2lpuA:
undetectable
1av2B-2lpuA:
undetectable		 1av2A-2lpuA:
8.26
1av2B-2lpuA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		3 / 3 ALA A 120
VAL A 122
TRP A 133
 None
 0.92A 1w5uA-2lpuA:
undetectable
1w5uB-2lpuA:
undetectable		 1w5uA-2lpuA:
8.26
1w5uB-2lpuA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		3 / 3 TRP A 133
ALA A 120
VAL A 122
 None
 1.00A 1w5uA-2lpuA:
undetectable
1w5uB-2lpuA:
undetectable		 1w5uA-2lpuA:
8.26
1w5uB-2lpuA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		4 / 8 LEU A  17
ILE A 134
ARG A  15
GLY A  33
 None
 0.91A 3b9lA-2lpuA:
undetectable		 3b9lA-2lpuA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		4 / 8 TRP A  21
THR A  19
ARG A  26
GLN A  35
 None
 1.32A 5tzoA-2lpuA:
undetectable		 5tzoA-2lpuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		4 / 8 TRP A  21
THR A  19
ARG A  26
GLN A  35
 None
 1.33A 5tzoC-2lpuA:
undetectable		 5tzoC-2lpuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		4 / 9 VAL A  55
HIS A  54
ASP A  53
SER A 101
 None
 0.80A 6c2mD-2lpuA:
undetectable		 6c2mD-2lpuA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2lpu KMATG10
(Kluyveromyces
marxianus) 		4 / 6 LEU A  17
TYR A   7
ASP A  29
GLN A  31
 None
 1.29A 6djzC-2lpuA:
undetectable		 6djzC-2lpuA:
22.17