SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lpv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 12 TYR A  27
PHE A  47
GLU A  55
VAL A  56
ILE A  57
ILE A  92
 None
 1.08A 1fapA-2lpvA:
18.2		 1fapA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 12 TYR A  27
PHE A  47
GLU A  55
VAL A  56
ILE A  57
TRP A  60
 None
 0.93A 1fapA-2lpvA:
18.2		 1fapA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
GLU A  55
VAL A  56
ILE A  57
TRP A  60
 None
 0.87A 1fkbA-2lpvA:
17.9		 1fkbA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
PHE A  47
GLU A  55
ILE A  57
TRP A  60
 None
 0.92A 1fkbA-2lpvA:
17.9		 1fkbA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
ILE A  57
TRP A  60
ILE A  92
PHE A 100
 None
 1.27A 1fkfA-2lpvA:
18.0		 1fkfA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.00A 1fkfA-2lpvA:
18.0		 1fkfA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.92A 1fkfA-2lpvA:
18.0		 1fkfA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 11 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.99A 1fkjA-2lpvA:
18.0		 1fkjA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 12 TYR A  27
GLU A  55
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.02A 1fklA-2lpvA:
17.8		 1fklA-2lpvA:
72.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 12 TYR A  27
PHE A  47
GLU A  55
ILE A  57
TRP A  60
ILE A  92
 None
 1.00A 1fklA-2lpvA:
17.8		 1fklA-2lpvA:
72.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
GLY A  54
VAL A  56
ILE A  57
TRP A  60
 None
 0.96A 1pbkA-2lpvA:
16.5		 1pbkA-2lpvA:
45.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 9 TYR A  27
ILE A  57
TRP A  60
ILE A  92
PHE A 100
 None
 1.29A 1q6iA-2lpvA:
13.9		 1q6iA-2lpvA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 9 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.02A 1q6iA-2lpvA:
13.9		 1q6iA-2lpvA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.00A 1q6iB-2lpvA:
13.4		 1q6iB-2lpvA:
32.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.07A 1yatA-2lpvA:
17.8		 1yatA-2lpvA:
51.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.04A 1yatA-2lpvA:
17.8		 1yatA-2lpvA:
51.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
GLU A  55
VAL A  56
ILE A  57
TRP A  60
 None
 0.87A 2dg3A-2lpvA:
17.8		 2dg3A-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
GLU A  55
ILE A  57
TRP A  60
 None
 0.91A 2dg3A-2lpvA:
17.8		 2dg3A-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
GLU A  55
VAL A  56
ILE A  57
ILE A  92
 None
 1.22A 2dg4A-2lpvA:
17.8		 2dg4A-2lpvA:
71.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 11 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.99A 2fkeA-2lpvA:
18.2		 2fkeA-2lpvA:
71.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
ILE A  57
TRP A  60
ILE A  92
PHE A 100
 None
 1.20A 3ihzA-2lpvA:
16.5		 3ihzA-2lpvA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 0.96A 3ihzA-2lpvA:
16.5		 3ihzA-2lpvA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.85A 3ihzA-2lpvA:
16.5		 3ihzA-2lpvA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		4 / 8 TYR A  27
PHE A  47
TRP A  60
ILE A  92
 None
 0.79A 3ihzB-2lpvA:
16.6		 3ihzB-2lpvA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
TRP A  60
ILE A  92
PHE A 100
 None
 1.19A 3o5rA-2lpvA:
16.2		 3o5rA-2lpvA:
41.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
 None
 0.90A 3o5rA-2lpvA:
16.2		 3o5rA-2lpvA:
41.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.09A 3uqaA-2lpvA:
16.4		 3uqaA-2lpvA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.02A 3uqaA-2lpvA:
16.4		 3uqaA-2lpvA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		4 / 8 TYR A  27
VAL A  56
ILE A  57
TRP A  60
 None
 0.84A 3uqbA-2lpvA:
16.0		 3uqbA-2lpvA:
29.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.03A 3vawA-2lpvA:
14.3		 3vawA-2lpvA:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.98A 3vawA-2lpvA:
14.3		 3vawA-2lpvA:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 12 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.06A 4drhD-2lpvA:
15.0		 4drhD-2lpvA:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 11 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.01A 4driA-2lpvA:
16.6		 4driA-2lpvA:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 11 TYR A  27
PHE A  47
GLU A  55
VAL A  56
ILE A  57
TRP A  60
 None
 0.86A 4drjA-2lpvA:
16.6		 4drjA-2lpvA:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 11 TYR A  27
PHE A  47
GLU A  55
VAL A  56
TRP A  60
ILE A  92
 None
 1.00A 4drjA-2lpvA:
16.6		 4drjA-2lpvA:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.07A 4dz2A-2lpvA:
16.1
4dz2B-2lpvA:
16.2		 4dz2A-2lpvA:
50.43
4dz2B-2lpvA:
50.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.05A 4dz2A-2lpvA:
16.1
4dz2B-2lpvA:
16.2		 4dz2A-2lpvA:
50.43
4dz2B-2lpvA:
50.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.09A 4dz2A-2lpvA:
16.1
4dz2B-2lpvA:
16.2		 4dz2A-2lpvA:
50.43
4dz2B-2lpvA:
50.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.07A 4dz2A-2lpvA:
16.1
4dz2B-2lpvA:
16.2		 4dz2A-2lpvA:
50.43
4dz2B-2lpvA:
50.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.11A 4dz3A-2lpvA:
16.3		 4dz3A-2lpvA:
51.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.06A 4dz3A-2lpvA:
16.3		 4dz3A-2lpvA:
51.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		4 / 7 LYS A  74
LEU A   8
THR A  28
SER A  39
 None
 1.06A 4ikjA-2lpvA:
undetectable
4ikjB-2lpvA:
undetectable		 4ikjA-2lpvA:
21.80
4ikjB-2lpvA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		4 / 7 LYS A  74
LEU A   8
THR A  28
SER A  39
 None
 1.10A 4iklA-2lpvA:
undetectable
4iklB-2lpvA:
undetectable		 4iklA-2lpvA:
21.80
4iklB-2lpvA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
 None
 0.90A 4laxA-2lpvA:
16.5		 4laxA-2lpvA:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.05A 4nnrA-2lpvA:
13.2
4nnrB-2lpvA:
13.2		 4nnrA-2lpvA:
39.01
4nnrB-2lpvA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.99A 4nnrA-2lpvA:
13.2
4nnrB-2lpvA:
13.2		 4nnrA-2lpvA:
39.01
4nnrB-2lpvA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
ILE A  57
TRP A  60
ILE A  92
PHE A 100
 None
 1.30A 4nnrB-2lpvA:
13.2		 4nnrB-2lpvA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.08A 4nnrB-2lpvA:
13.2		 4nnrB-2lpvA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.05A 4nnrB-2lpvA:
13.2		 4nnrB-2lpvA:
39.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 GLU A  55
VAL A  56
ILE A  57
TYR A  83
ILE A  92
 None
 1.26A 4qt2A-2lpvA:
16.7		 4qt2A-2lpvA:
39.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		7 / 10 TYR A  27
PHE A  47
GLU A  55
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.00A 4qt2A-2lpvA:
16.7		 4qt2A-2lpvA:
39.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 GLU A  55
VAL A  56
ILE A  57
TYR A  83
ILE A  92
 None
 1.18A 4qt3A-2lpvA:
15.5		 4qt3A-2lpvA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		7 / 10 TYR A  27
PHE A  47
GLU A  55
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.97A 4qt3A-2lpvA:
15.5		 4qt3A-2lpvA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.11A 5b8iC-2lpvA:
16.3		 5b8iC-2lpvA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.10A 5b8iC-2lpvA:
16.3		 5b8iC-2lpvA:
41.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.98A 5d75A-2lpvA:
16.5		 5d75A-2lpvA:
45.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.02A 5gpgA-2lpvA:
17.2		 5gpgA-2lpvA:
45.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
VAL A  56
TRP A  60
ILE A  92
 None
 1.00A 5hw8B-2lpvA:
16.2		 5hw8B-2lpvA:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 11 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.00A 5hw8D-2lpvA:
16.6		 5hw8D-2lpvA:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
 None
 0.95A 5hw8E-2lpvA:
16.2		 5hw8E-2lpvA:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
 None
 0.85A 5hw8B-2lpvA:
16.2
5hw8F-2lpvA:
13.0
5hw8G-2lpvA:
15.7		 5hw8B-2lpvA:
46.67
5hw8F-2lpvA:
46.67
5hw8G-2lpvA:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.04A 5hw8G-2lpvA:
15.7		 5hw8G-2lpvA:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.08A 5hw8G-2lpvA:
15.7		 5hw8G-2lpvA:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 1.02A 5hwcA-2lpvA:
17.8		 5hwcA-2lpvA:
52.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 11 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 1.05A 5hwcA-2lpvA:
17.8		 5hwcA-2lpvA:
52.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		4 / 7 LEU A  31
GLY A  29
LEU A  75
GLY A  59
 None
 0.81A 6eu9D-2lpvA:
undetectable		 6eu9D-2lpvA:
25.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		6 / 12 TYR A  27
PHE A  47
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.94A 6mkeA-2lpvA:
17.1
6mkeD-2lpvA:
17.1		 6mkeA-2lpvA:
43.75
6mkeD-2lpvA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 0.90A 6mkeB-2lpvA:
17.0
6mkeC-2lpvA:
17.3		 6mkeB-2lpvA:
43.75
6mkeC-2lpvA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 12 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.88A 6mkeB-2lpvA:
17.0
6mkeC-2lpvA:
17.3		 6mkeB-2lpvA:
43.75
6mkeC-2lpvA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 0.94A 6mkeC-2lpvA:
17.3		 6mkeC-2lpvA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.95A 6mkeC-2lpvA:
17.3		 6mkeC-2lpvA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
PHE A  47
ILE A  57
TRP A  60
ILE A  92
 None
 0.95A 6mkeD-2lpvA:
17.1		 6mkeD-2lpvA:
43.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Aedes
aegypti) 		5 / 10 TYR A  27
VAL A  56
ILE A  57
TRP A  60
ILE A  92
 None
 0.92A 6mkeD-2lpvA:
17.1		 6mkeD-2lpvA:
43.75