SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 2lq6 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		3 / 3 CYH A 346
CYH A 385
HIS A 388
 ZN  A 402 (-2.1A)
ZN  A 402 (-2.1A)
ZN  A 402 (-3.3A)
 0.82A 2iwkA-2lq6A:
undetectable		 2iwkA-2lq6A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 2lq6 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		3 / 3 CYH A 346
CYH A 385
HIS A 388
 ZN  A 402 (-2.1A)
ZN  A 402 (-2.1A)
ZN  A 402 (-3.3A)
 0.81A 2iwkB-2lq6A:
undetectable		 2iwkB-2lq6A:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2lq6 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		4 / 7 TYR A 328
PHE A 350
ALA A 383
ALA A 355
 None
 1.00A 2vcvA-2lq6A:
undetectable		 2vcvA-2lq6A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2lq6 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		3 / 3 CYH A 346
CYH A 385
HIS A 388
 ZN  A 402 (-2.1A)
ZN  A 402 (-2.1A)
ZN  A 402 (-3.3A)
 0.78A 3dtuB-2lq6A:
undetectable		 3dtuB-2lq6A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2lq6 BROMODOMAIN-CONTAINI
NG PROTEIN 1
(Homo
sapiens) 		3 / 3 CYH A 346
CYH A 385
HIS A 388
 ZN  A 402 (-2.1A)
ZN  A 402 (-2.1A)
ZN  A 402 (-3.3A)
 0.76A 3dtuD-2lq6A:
undetectable		 3dtuD-2lq6A:
14.94