SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 2lqg TALIN-1
(Mus
musculus) 		6 / 11 ALA A 920
LEU A 917
LEU A1034
LEU A 994
SER A 992
ALA A 989
 None
 1.48A 1h9zA-2lqgA:
2.2		 1h9zA-2lqgA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 2lqg TALIN-1
(Mus
musculus) 		6 / 11 ALA A 920
LEU A 917
LEU A1034
LEU A 994
SER A 992
ALA A 989
 None
 1.45A 1ha2A-2lqgA:
undetectable		 1ha2A-2lqgA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 2lqg TALIN-1
(Mus
musculus) 		5 / 12 GLY A 998
GLY A 997
LEU A1027
SER A 927
LEU A 966
 None
 1.03A 1ya4C-2lqgA:
undetectable		 1ya4C-2lqgA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 4 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.28A 5n0rA-2lqgA:
undetectable		 5n0rA-2lqgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 4 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.28A 5n0sA-2lqgA:
undetectable		 5n0sA-2lqgA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 5 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.24A 5n0tA-2lqgA:
undetectable		 5n0tA-2lqgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 4 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.29A 5n0wA-2lqgA:
undetectable		 5n0wA-2lqgA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 5 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.32A 5n0wB-2lqgA:
undetectable		 5n0wB-2lqgA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 4 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.32A 5n0xA-2lqgA:
undetectable		 5n0xA-2lqgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2lqg TALIN-1
(Mus
musculus) 		4 / 5 SER A1007
ALA A1004
GLN A1019
THR A 931
 None
 1.34A 5n4iA-2lqgA:
undetectable		 5n4iA-2lqgA:
18.70