SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 GLN A 169
LEU A 207
SER A 172
ASN A 174
 None
 1.15A 1ig3A-2lqjA:
undetectable
1ig3B-2lqjA:
undetectable		 1ig3A-2lqjA:
19.60
1ig3B-2lqjA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 THR A 192
PRO A 185
THR A 183
 None
 0.79A 209dC-2lqjA:
undetectable		 209dC-2lqjA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 THR A 171
LEU A 197
VAL A 151
VAL A 163
 None
 1.04A 2zuhA-2lqjA:
undetectable		 2zuhA-2lqjA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 THR A 171
LEU A 197
VAL A 151
VAL A 163
 None
 1.06A 2zuiA-2lqjA:
undetectable		 2zuiA-2lqjA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 207
LEU A 197
SER A 172
ASN A 174
 None
 1.03A 3lm8A-2lqjA:
undetectable
3lm8C-2lqjA:
undetectable		 3lm8A-2lqjA:
14.29
3lm8C-2lqjA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 207
LEU A 197
SER A 172
ASN A 174
 None
 1.06A 3lm8B-2lqjA:
undetectable
3lm8D-2lqjA:
undetectable		 3lm8B-2lqjA:
14.29
3lm8D-2lqjA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2lqj MG2+ TRANSPORT
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 ILE A 167
ILE A 176
SER A 215
VAL A 223
 None
 0.87A 3ua5A-2lqjA:
undetectable		 3ua5A-2lqjA:
12.65