SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		3 / 3 LYS A  45
TYR A  44
ARG A  48
 None
 1.36A 4gc9A-2lqtA:
undetectable		 4gc9A-2lqtA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		5 / 12 ILE A  54
ARG A  73
PRO A  84
PHE A  50
ARG A  49
 None
 1.26A 5il1A-2lqtA:
undetectable		 5il1A-2lqtA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		4 / 6 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.46A 5x7pA-2lqtA:
undetectable		 5x7pA-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		4 / 6 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.46A 5x7pB-2lqtA:
undetectable		 5x7pB-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		4 / 6 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.45A 5x7qA-2lqtA:
undetectable		 5x7qA-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		4 / 6 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.40A 5x7qB-2lqtA:
undetectable		 5x7qB-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		4 / 6 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.47A 5x7rA-2lqtA:
undetectable		 5x7rA-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7
(Homo
sapiens) 		4 / 6 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.45A 5x7rB-2lqtA:
undetectable		 5x7rB-2lqtA:
4.96