SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A  76
VAL A 111
TYR A 105
TYR A 109
PHE A 118
 None
 1.11A 2zd1A-2lrtA:
undetectable		 2zd1A-2lrtA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 GLU A 145
HIS A 151
HIS A 150
 None
 0.88A 3co4A-2lrtA:
undetectable		 3co4A-2lrtA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A  72
TYR A 109
ILE A  16
 None
 0.77A 3eteA-2lrtA:
undetectable
3eteB-2lrtA:
undetectable		 3eteA-2lrtA:
14.77
3eteB-2lrtA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A  76
VAL A 111
TYR A 105
TYR A 109
PHE A 118
 None
 1.08A 4iclA-2lrtA:
1.4		 4iclA-2lrtA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A  76
VAL A 111
TYR A 105
TYR A 109
PHE A 118
 None
 1.10A 4ifyA-2lrtA:
undetectable		 4ifyA-2lrtA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A  76
VAL A 111
TYR A 105
TYR A 109
PHE A 118
 None
 1.08A 4kfbA-2lrtA:
undetectable		 4kfbA-2lrtA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A  76
VAL A 111
TYR A 105
TYR A 109
PHE A 118
 None
 1.06A 6eliA-2lrtA:
undetectable		 6eliA-2lrtA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 111
GLU A 131
LEU A   3
SER A 116
LEU A  30
 None
 1.08A 6ew0B-2lrtA:
undetectable		 6ew0B-2lrtA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 111
GLU A 131
LEU A   3
SER A 116
LEU A  30
 None
 1.08A 6ew0D-2lrtA:
undetectable		 6ew0D-2lrtA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 111
GLU A 131
LEU A   3
SER A 116
LEU A  30
 None
 1.08A 6ew0H-2lrtA:
undetectable		 6ew0H-2lrtA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 2lrt UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 VAL A 111
GLU A 131
LEU A   3
SER A 116
LEU A  30
 None
 1.07A 6ew0I-2lrtA:
undetectable		 6ew0I-2lrtA:
19.87