SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ls5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_B_SAMB801_0 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	2ls5	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	5 / 12	GLY A 73 GLY A 97 ASP A 75 LEU A 20 LEU A 71	None	1.07A	2zw9B-2ls5A: undetectable	2zw9B-2ls5A: 11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_B_ACTB4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	2ls5	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	3 / 3	GLY A 73 GLY A 97 THR A 21	None	0.44A	3si7B-2ls5A: undetectable	3si7B-2ls5A: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BC9_A_ETSA302_2 (CARBONIC ANHYDRASE 2)	2ls5	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	4 / 5	HIS A 157 GLU A 152 HIS A 154 VAL A 128	None	1.13A	6bc9A-2ls5A: undetectable	6bc9A-2ls5A: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_D_NMYD302_0 (AAC(3)-IIIB PROTEIN)	2ls5	UNCHARACTERIZED PROTEIN (Bacteroides thetaiotaomicron)	5 / 10	ASP A 15 TYR A 108 GLY A 125 ASP A 122 GLU A 124	None	1.44A	6mb9D-2ls5A: undetectable	6mb9D-2ls5A: 20.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZW9_B_SAMB801_0","LEUCINE CARBOXYL METHYLTRANSFERASE 2","2ls5","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",5,"GLY A  73;GLY A  97;ASP A  75;LEU A  20;LEU A  71","None","1.07A","2zw9B-2ls5A:undetectable","2zw9B-2ls5A:11.94"],["3SI7_B_ACTB4_0","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","2ls5","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",3,"GLY A  73;GLY A  97;THR A  21","None","0.44A","3si7B-2ls5A:undetectable","3si7B-2ls5A:20.35"],["6BC9_A_ETSA302_2","CARBONIC ANHYDRASE 2","2ls5","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",4,"HIS A 157;GLU A 152;HIS A 154;VAL A 128","None","1.13A","6bc9A-2ls5A:undetectable","6bc9A-2ls5A:21.29"],["6MB9_D_NMYD302_0","AAC(3)-IIIB PROTEIN","2ls5","UNCHARACTERIZED PROTEIN","Bacteroides thetaiotaomicron",5,"ASP A  15;TYR A 108;GLY A 125;ASP A 122;GLU A 124","None","1.44A","6mb9D-2ls5A:undetectable","6mb9D-2ls5A:20.78"]]