SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 2lsj DNA REPAIR PROTEIN
REV1
(Mus
musculus) 		3 / 3 ARG A  83
TYR A  80
LYS A  37
 None
 0.97A 1uujB-2lsjA:
undetectable		 1uujB-2lsjA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 2lsj DNA REPAIR PROTEIN
REV1
(Mus
musculus) 		5 / 12 LEU A  65
MET A  81
LEU A  27
ILE A  55
LEU A 101
 None
 1.24A 2j7xA-2lsjA:
undetectable		 2j7xA-2lsjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2lsj DNA REPAIR PROTEIN
REV1
(Mus
musculus) 		5 / 12 MET A  85
ILE A  44
ALA A  96
LEU A  40
LEU A 116
 None
 1.10A 2rctA-2lsjA:
undetectable		 2rctA-2lsjA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2lsj DNA REPAIR PROTEIN
REV1
(Mus
musculus) 		5 / 12 MET A  85
ILE A  44
ALA A  96
LEU A  40
LEU A 116
 None
 0.97A 4qynA-2lsjA:
undetectable		 4qynA-2lsjA:
23.29