SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lsn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 2lsn RNASE H
(Simian
foamy
virus) 		5 / 12 LEU A  95
LEU A 111
ILE A 120
SER A 115
LYS A 118
 None
 1.45A 1lbcA-2lsnA:
undetectable
1lbcC-2lsnA:
undetectable		 1lbcA-2lsnA:
22.57
1lbcC-2lsnA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 2lsn RNASE H
(Simian
foamy
virus) 		5 / 12 LEU A  95
LEU A 111
ILE A 120
SER A 115
LYS A 118
 None
 1.34A 3iltB-2lsnA:
undetectable
3iltE-2lsnA:
undetectable		 3iltB-2lsnA:
22.05
3iltE-2lsnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 ASP A  13
ASN A 150
SER A  15
 None
 0.92A 3lslA-2lsnA:
undetectable
3lslD-2lsnA:
undetectable		 3lslA-2lsnA:
22.05
3lslD-2lsnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  15
ASP A  13
ASN A 150
 None
 0.90A 3lslA-2lsnA:
1.2
3lslD-2lsnA:
undetectable		 3lslA-2lsnA:
22.05
3lslD-2lsnA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.88A 4k8cA-2lsnA:
undetectable		 4k8cA-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.85A 4kahA-2lsnA:
undetectable		 4kahA-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.85A 4kahB-2lsnA:
undetectable		 4kahB-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.87A 4kanA-2lsnA:
undetectable		 4kanA-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.89A 4kanB-2lsnA:
undetectable		 4kanB-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.89A 4kbeA-2lsnA:
undetectable		 4kbeA-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.87A 4kbeB-2lsnA:
undetectable		 4kbeB-2lsnA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2lsn RNASE H
(Simian
foamy
virus) 		3 / 3 SER A  90
TYR A  86
PRO A  96
 None
 0.86A 4lbgB-2lsnA:
undetectable		 4lbgB-2lsnA:
18.37