SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lt3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2lt3 TRANSCRIPTIONAL
REGULATOR, CARD
FAMILY
(Myxococcus
xanthus) 		5 / 12 GLY A  75
GLU A  76
LEU A  66
ASP A  62
ASN A  38
 None
 1.20A 1qzzA-2lt3A:
undetectable		 1qzzA-2lt3A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 2lt3 TRANSCRIPTIONAL
REGULATOR, CARD
FAMILY
(Myxococcus
xanthus) 		5 / 12 GLY A  75
GLU A  76
LEU A  66
ASP A  62
ASN A  38
 None
 1.09A 1xdsA-2lt3A:
undetectable		 1xdsA-2lt3A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 2lt3 TRANSCRIPTIONAL
REGULATOR, CARD
FAMILY
(Myxococcus
xanthus) 		5 / 12 GLY A  75
GLU A  76
LEU A  66
ASP A  62
ASN A  38
 None
 1.11A 1xdsB-2lt3A:
undetectable		 1xdsB-2lt3A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2lt3 TRANSCRIPTIONAL
REGULATOR, CARD
FAMILY
(Myxococcus
xanthus) 		4 / 6 ARG A  84
SER A  85
ARG A  77
GLU A  99
 None
 1.41A 2c8aC-2lt3A:
undetectable		 2c8aC-2lt3A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2lt3 TRANSCRIPTIONAL
REGULATOR, CARD
FAMILY
(Myxococcus
xanthus) 		5 / 9 LEU A 106
ILE A 109
LEU A  91
ILE A 102
TYR A  22
 None
 1.27A 2f7aA-2lt3A:
undetectable		 2f7aA-2lt3A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2lt3 TRANSCRIPTIONAL
REGULATOR, CARD
FAMILY
(Myxococcus
xanthus) 		5 / 11 ILE A 102
LEU A  60
ILE A  56
VAL A  21
ILE A  13
 None
 1.02A 3b2rB-2lt3A:
undetectable		 3b2rB-2lt3A:
17.33