SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lt5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WG8_A_SAMA3142_0 (PREDICTED S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	2lt5	PROTEIN P-30 (Rana pipiens)	5 / 12	GLY A 35 GLY A 36 GLY A 38 PHE A 26 SER A 34	None	1.18A	1wg8A-2lt5A: undetectable	1wg8A-2lt5A: 16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_B_ACTB901_0 (PYRANOSE 2-OXIDASE)	2lt5	PROTEIN P-30 (Rana pipiens)	4 / 6	SER A 87 PHE A 14 PHE A 54 HIS A 58	None	1.27A	3lskB-2lt5A: undetectable	3lskB-2lt5A: 11.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SNF_A_ACTA110_0 (PROTEIN P-30)	2lt5	PROTEIN P-30 (Rana pipiens)	4 / 5	ILE A 95 THR A 107 THR A 108 PHE A 14	None	1.16A	3snfA-2lt5A: 5.0	3snfA-2lt5A: 70.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SNF_A_ACTA110_0 (PROTEIN P-30)	2lt5	PROTEIN P-30 (Rana pipiens)	4 / 5	ILE A 95 THR A 107 THR A 108 SER A 109	None	0.72A	3snfA-2lt5A: 5.0	3snfA-2lt5A: 70.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SNF_A_ACTA110_0 (PROTEIN P-30)	2lt5	PROTEIN P-30 (Rana pipiens)	4 / 5	THR A 107 THR A 108 SER A 109 PHE A 111	None	0.97A	3snfA-2lt5A: 5.0	3snfA-2lt5A: 70.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WG8_A_SAMA3142_0","PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","2lt5","PROTEIN P-30","Rana pipiens",5,"GLY A  35;GLY A  36;GLY A  38;PHE A  26;SER A  34","None","1.18A","1wg8A-2lt5A:undetectable","1wg8A-2lt5A:16.91"],["3LSK_B_ACTB901_0","PYRANOSE 2-OXIDASE","2lt5","PROTEIN P-30","Rana pipiens",4,"SER A  87;PHE A  14;PHE A  54;HIS A  58","None","1.27A","3lskB-2lt5A:undetectable","3lskB-2lt5A:11.28"],["3SNF_A_ACTA110_0","PROTEIN P-30","2lt5","PROTEIN P-30","Rana pipiens",4,"ILE A  95;THR A 107;THR A 108;PHE A  14","None","1.16A","3snfA-2lt5A:5.0","3snfA-2lt5A:70.59"],["3SNF_A_ACTA110_0","PROTEIN P-30","2lt5","PROTEIN P-30","Rana pipiens",4,"ILE A  95;THR A 107;THR A 108;SER A 109","None","0.72A","3snfA-2lt5A:5.0","3snfA-2lt5A:70.59"],["3SNF_A_ACTA110_0","PROTEIN P-30","2lt5","PROTEIN P-30","Rana pipiens",4,"THR A 107;THR A 108;SER A 109;PHE A 111","None","0.97A","3snfA-2lt5A:5.0","3snfA-2lt5A:70.59"]]