SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 2lu2 MICRONEME TGMIC5
PROTEIN
(Toxoplasma
gondii) 		4 / 7 VAL A  64
THR A  65
PHE A  73
LYS A  75
 None
 1.16A 2kotA-2lu2A:
undetectable		 2kotA-2lu2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 2lu2 MICRONEME TGMIC5
PROTEIN
(Toxoplasma
gondii) 		4 / 7 HIS A 120
GLY A 127
ALA A 125
PHE A  73
 None
 0.98A 3tehB-2lu2A:
3.1		 3tehB-2lu2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2lu2 MICRONEME TGMIC5
PROTEIN
(Toxoplasma
gondii) 		5 / 12 GLY A  91
THR A 109
ILE A 122
VAL A 129
ILE A 104
 None
 0.88A 6emuA-2lu2A:
undetectable		 6emuA-2lu2A:
24.26