SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		4 / 6 ILE A  86
MET A  41
ILE A  35
HIS A 101
 None
 1.19A 3eteA-2lv3A:
undetectable
3eteE-2lv3A:
undetectable		 3eteA-2lv3A:
13.24
3eteE-2lv3A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		4 / 5 ILE A  86
MET A  41
ILE A  35
HIS A 101
 None
 1.18A 3eteB-2lv3A:
undetectable
3eteC-2lv3A:
undetectable		 3eteB-2lv3A:
13.24
3eteC-2lv3A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		4 / 8 LEU A  27
GLU A  81
THR A  84
VAL A  92
 None
 0.92A 4iizB-2lv3A:
undetectable		 4iizB-2lv3A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		5 / 12 LEU A 117
VAL A  63
VAL A  97
TYR A  65
LEU A  57
 None
 1.40A 5cymA-2lv3A:
undetectable		 5cymA-2lv3A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		5 / 12 LEU A 117
VAL A  63
VAL A  97
TYR A  65
LEU A  57
 None
 1.40A 5cyqA-2lv3A:
undetectable		 5cyqA-2lv3A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		3 / 3 GLY A 103
GLY A 104
GLN A  89
 None
 0.50A 5imsA-2lv3A:
undetectable		 5imsA-2lv3A:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2lv3 THIOREDOXIN
REDUCTASE 3
(Mus
musculus) 		5 / 12 LEU A 117
VAL A  63
VAL A  97
TYR A  65
LEU A  57
 None
 1.43A 6eliA-2lv3A:
undetectable		 6eliA-2lv3A:
19.84