SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2lv4 PUTATIVE OUTER
MEMBRANE OR EXPORTED
PROTEIN
(Salmonella
enterica) 		5 / 11 ILE A 258
ILE A 272
VAL A 219
ASN A 223
GLU A 254
 None
 0.89A 5lg3A-2lv4A:
undetectable		 5lg3A-2lv4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2lv4 PUTATIVE OUTER
MEMBRANE OR EXPORTED
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 258
ILE A 272
VAL A 219
ASN A 223
GLU A 254
 None
 0.87A 5lg3E-2lv4A:
undetectable		 5lg3E-2lv4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2lv4 PUTATIVE OUTER
MEMBRANE OR EXPORTED
PROTEIN
(Salmonella
enterica) 		5 / 10 ILE A 258
ILE A 272
VAL A 219
ASN A 223
GLU A 254
 None
 0.93A 5lg3F-2lv4A:
undetectable		 5lg3F-2lv4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2lv4 PUTATIVE OUTER
MEMBRANE OR EXPORTED
PROTEIN
(Salmonella
enterica) 		5 / 10 ILE A 258
ILE A 272
VAL A 219
ASN A 223
GLU A 254
 None
 0.84A 5lg3G-2lv4A:
undetectable		 5lg3G-2lv4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2lv4 PUTATIVE OUTER
MEMBRANE OR EXPORTED
PROTEIN
(Salmonella
enterica) 		5 / 10 ILE A 258
ILE A 272
VAL A 219
ASN A 223
GLU A 254
 None
 0.82A 5lg3H-2lv4A:
undetectable		 5lg3H-2lv4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2lv4 PUTATIVE OUTER
MEMBRANE OR EXPORTED
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 258
ILE A 272
VAL A 219
ASN A 223
GLU A 254
 None
 0.87A 5lg3J-2lv4A:
undetectable		 5lg3J-2lv4A:
19.86