SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD6_0
(GRAMICIDIN A)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  91
TRP A  95
ALA A  35
VAL A  97
 None
 1.42A 1gmkC-2lv5A:
undetectable
1gmkD-2lv5A:
undetectable		 1gmkC-2lv5A:
14.49
1gmkD-2lv5A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.96A 1ra8A-2lv5A:
undetectable		 1ra8A-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 VAL A  96
VAL A  97
GLN A  99
PHE A  31
 None
 1.29A 3bjwH-2lv5A:
undetectable		 3bjwH-2lv5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  96
VAL A  97
GLN A  99
PHE A  31
 None
 1.22A 3bjwF-2lv5A:
undetectable		 3bjwF-2lv5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 VAL A  96
VAL A  97
GLN A  99
PHE A  31
 None
 1.33A 3bjwB-2lv5A:
undetectable		 3bjwB-2lv5A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLU A  50
VAL A  60
VAL A  92
ALA A  53
 None
 1.04A 3kp6B-2lv5A:
undetectable		 3kp6B-2lv5A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  11
GLU A   6
SER A   9
 None
 0.76A 4ccqA-2lv5A:
undetectable		 4ccqA-2lv5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.90A 4ej1A-2lv5A:
undetectable		 4ej1A-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  47
ASP A  44
ASP A  40
 None
 0.58A 4gc9A-2lv5A:
undetectable		 4gc9A-2lv5A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.91A 4i13A-2lv5A:
undetectable		 4i13A-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.94A 4kjjA-2lv5A:
undetectable		 4kjjA-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 1.00A 4kjkA-2lv5A:
undetectable		 4kjkA-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  16
ASP A  56
GLU A  47
VAL A  97
 None
 1.11A 4nkvA-2lv5A:
undetectable		 4nkvA-2lv5A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 1.00A 4nx6A-2lv5A:
undetectable		 4nx6A-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.97A 4nx7A-2lv5A:
undetectable		 4nx7A-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.98A 4p3qA-2lv5A:
undetectable		 4p3qA-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.97A 4p3rA-2lv5A:
undetectable		 4p3rA-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.96A 4pssA-2lv5A:
undetectable		 4pssA-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.97A 4pthA-2lv5A:
undetectable		 4pthA-2lv5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 0.91A 4x5iA-2lv5A:
undetectable		 4x5iA-2lv5A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  37
VAL A  48
GLU A  47
VAL A  60
 None
 1.20A 5jh7C-2lv5A:
undetectable		 5jh7C-2lv5A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 1.00A 5z6kA-2lv5A:
undetectable		 5z6kA-2lv5A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2lv5 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  49
TRP A  95
ILE A  22
LEU A  27
ILE A  98
 None
 1.03A 7dfrA-2lv5A:
undetectable		 7dfrA-2lv5A:
22.56