SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2lvc OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A  19
THR A  67
PRO A  69
 None
 0.85A 1a7yA-2lvcA:
undetectable		 1a7yA-2lvcA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2lvc OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A  67
PRO A  69
THR A  19
 None
 0.86A 1ovfB-2lvcA:
undetectable		 1ovfB-2lvcA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2lvc OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A  19
THR A  67
PRO A  69
 None
 0.85A 1qfiA-2lvcA:
undetectable		 1qfiA-2lvcA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 2lvc OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A  30
ARG A  31
ASP A  81
 None
 0.81A 4fp9D-2lvcA:
undetectable		 4fp9D-2lvcA:
14.57