SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lwf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJ8_C_SPMC500_1 (DIAMINE ACETYLTRANSFERASE 1)	2lwf	MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC (Arabidopsis thaliana)	4 / 6	ASP A 97 LEU A 99 LEU A 116 HIS A 115	None	1.26A	3bj8C-2lwfA: 1.2 3bj8D-2lwfA: 1.3	3bj8C-2lwfA: 20.35 3bj8D-2lwfA: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGL_A_RZXA257_1 (CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1)	2lwf	MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC (Arabidopsis thaliana)	4 / 7	VAL A 126 ILE A 77 SER A 111 TYR A 90	None	0.96A	3pglA-2lwfA: undetectable	3pglA-2lwfA: 23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M48_A_21BA704_1 (TRANSPORTER)	2lwf	MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC (Arabidopsis thaliana)	4 / 8	VAL A 128 TYR A 90 SER A 105 GLY A 88	None	0.91A	4m48A-2lwfA: undetectable	4m48A-2lwfA: 11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6JNH_A_ASCA201_0 (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE)	2lwf	MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC (Arabidopsis thaliana)	4 / 7	GLY A 103 PHE A 101 HIS A 115 SER A 113	None	0.83A	6jnhA-2lwfA: undetectable	6jnhA-2lwfA: 22.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJ8_C_SPMC500_1","DIAMINE ACETYLTRANSFERASE 1;DIAMINE ACETYLTRANSFERASE 1","2lwf","MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC","Arabidopsis thaliana",4,"ASP A  97;LEU A  99;LEU A 116;HIS A 115","None","1.26A","3bj8C-2lwfA:1.2;3bj8D-2lwfA:1.3","3bj8C-2lwfA:20.35;3bj8D-2lwfA:20.35"],["3PGL_A_RZXA257_1","CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1","2lwf","MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC","Arabidopsis thaliana",4,"VAL A 126;ILE A  77;SER A 111;TYR A  90","None","0.96A","3pglA-2lwfA:undetectable","3pglA-2lwfA:23.91"],["4M48_A_21BA704_1","TRANSPORTER","2lwf","MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC","Arabidopsis thaliana",4,"VAL A 128;TYR A  90;SER A 105;GLY A  88","None","0.91A","4m48A-2lwfA:undetectable","4m48A-2lwfA:11.42"],["6JNH_A_ASCA201_0","PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE","2lwf","MONOTHIOL GLUTAREDOXIN-S16, CHLOROPLASTIC","Arabidopsis thaliana",4,"GLY A 103;PHE A 101;HIS A 115;SER A 113","None","0.83A","6jnhA-2lwfA:undetectable","6jnhA-2lwfA:22.70"]]