SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2lwx ZUOTIN
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 424
PRO A 425
LEU A 428
 None
 0.44A 1hrkA-2lwxA:
undetectable		 1hrkA-2lwxA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2lwx ZUOTIN
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 368
LEU A 411
VAL A 381
VAL A 394
ALA A 397
 None
 1.21A 1q23H-2lwxA:
undetectable
1q23I-2lwxA:
undetectable		 1q23H-2lwxA:
21.03
1q23I-2lwxA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2lwx ZUOTIN
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 424
PRO A 425
LEU A 428
 None
 0.48A 3w1wB-2lwxA:
undetectable		 3w1wB-2lwxA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2lwx ZUOTIN
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 425
LEU A 424
GLN A 380
 None
 0.44A 4pevB-2lwxA:
undetectable		 4pevB-2lwxA:
12.88