SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BX4_A_ADNA350_2 (PROTEIN (ADENOSINE KINASE))	2lwy	BACTERIAL INTEIN-LIKE DOMAIN (Ruminiclostridiu m thermocellum)	3 / 3	LEU A 90 SER A 92 ASN A 129	None	0.84A	1bx4A-2lwyA: undetectable	1bx4A-2lwyA: 16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_A_EAAA223_1 (GLUTATHIONE TRANSFERASE A1-1)	2lwy	BACTERIAL INTEIN-LIKE DOMAIN (Ruminiclostridiu m thermocellum)	4 / 8	GLY A 127 LEU A 14 VAL A 26 PHE A 2	None	1.23A	1gsfA-2lwyA: undetectable	1gsfA-2lwyA: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_B_EAAB223_1 (GLUTATHIONE TRANSFERASE A1-1)	2lwy	BACTERIAL INTEIN-LIKE DOMAIN (Ruminiclostridiu m thermocellum)	4 / 8	GLY A 127 LEU A 14 VAL A 26 PHE A 2	None	1.23A	1gsfB-2lwyA: undetectable	1gsfB-2lwyA: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSF_D_EAAD223_1 (GLUTATHIONE TRANSFERASE A1-1)	2lwy	BACTERIAL INTEIN-LIKE DOMAIN (Ruminiclostridiu m thermocellum)	4 / 8	GLY A 127 LEU A 14 VAL A 26 PHE A 2	None	1.23A	1gsfD-2lwyA: undetectable	1gsfD-2lwyA: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_A_NCAA300_0 (PROTOGLOBIN)	2lwy	BACTERIAL INTEIN-LIKE DOMAIN (Ruminiclostridiu m thermocellum)	4 / 7	VAL A 99 VAL A 78 PHE A 70 ILE A 62	None	0.88A	3zjqA-2lwyA: undetectable	3zjqA-2lwyA: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_B_NCAB300_0 (PROTOGLOBIN)	2lwy	BACTERIAL INTEIN-LIKE DOMAIN (Ruminiclostridiu m thermocellum)	4 / 7	VAL A 99 VAL A 78 PHE A 70 ILE A 62	None	0.89A	3zjqB-2lwyA: undetectable	3zjqB-2lwyA: 21.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BX4_A_ADNA350_2","PROTEIN (ADENOSINE KINASE)","2lwy","BACTERIAL INTEIN-LIKE DOMAIN","Ruminiclostridium thermocellum",3,"LEU A  90;SER A  92;ASN A 129","None","0.84A","1bx4A-2lwyA:undetectable","1bx4A-2lwyA:16.98"],["1GSF_A_EAAA223_1","GLUTATHIONE TRANSFERASE A1-1","2lwy","BACTERIAL INTEIN-LIKE DOMAIN","Ruminiclostridium thermocellum",4,"GLY A 127;LEU A  14;VAL A  26;PHE A   2","None","1.23A","1gsfA-2lwyA:undetectable","1gsfA-2lwyA:22.58"],["1GSF_B_EAAB223_1","GLUTATHIONE TRANSFERASE A1-1","2lwy","BACTERIAL INTEIN-LIKE DOMAIN","Ruminiclostridium thermocellum",4,"GLY A 127;LEU A  14;VAL A  26;PHE A   2","None","1.23A","1gsfB-2lwyA:undetectable","1gsfB-2lwyA:22.58"],["1GSF_D_EAAD223_1","GLUTATHIONE TRANSFERASE A1-1","2lwy","BACTERIAL INTEIN-LIKE DOMAIN","Ruminiclostridium thermocellum",4,"GLY A 127;LEU A  14;VAL A  26;PHE A   2","None","1.23A","1gsfD-2lwyA:undetectable","1gsfD-2lwyA:22.58"],["3ZJQ_A_NCAA300_0","PROTOGLOBIN","2lwy","BACTERIAL INTEIN-LIKE DOMAIN","Ruminiclostridium thermocellum",4,"VAL A  99;VAL A  78;PHE A  70;ILE A  62","None","0.88A","3zjqA-2lwyA:undetectable","3zjqA-2lwyA:21.61"],["3ZJQ_B_NCAB300_0","PROTOGLOBIN","2lwy","BACTERIAL INTEIN-LIKE DOMAIN","Ruminiclostridium thermocellum",4,"VAL A  99;VAL A  78;PHE A  70;ILE A  62","None","0.89A","3zjqB-2lwyA:undetectable","3zjqB-2lwyA:21.61"]]