SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lxj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2lxj COLD SHOCK-LIKE
PROTEIN CSPLA
(Listeria
monocytogenes) 		4 / 8 PHE A  15
GLY A  16
GLU A  43
ILE A  33
 None
 0.86A 3aodA-2lxjA:
undetectable		 3aodA-2lxjA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2lxj COLD SHOCK-LIKE
PROTEIN CSPLA
(Listeria
monocytogenes) 		4 / 8 PHE A  27
GLU A  43
ALA A  60
PHE A  30
 None
 0.96A 3aodA-2lxjA:
undetectable		 3aodA-2lxjA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2lxj COLD SHOCK-LIKE
PROTEIN CSPLA
(Listeria
monocytogenes) 		4 / 5 PHE A  49
ILE A  18
GLN A   3
ARG A  20
 None
 1.44A 5jm4A-2lxjA:
undetectable		 5jm4A-2lxjA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2lxj COLD SHOCK-LIKE
PROTEIN CSPLA
(Listeria
monocytogenes) 		4 / 4 PHE A  49
ILE A  18
GLN A   3
ARG A  20
 None
 1.39A 5jm4B-2lxjA:
undetectable		 5jm4B-2lxjA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 2lxj COLD SHOCK-LIKE
PROTEIN CSPLA
(Listeria
monocytogenes) 		5 / 12 GLN A  45
ALA A  46
GLY A   4
LEU A  41
ASP A  25
 None
 1.45A 5vlmF-2lxjA:
undetectable		 5vlmF-2lxjA:
19.05