SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ly2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2ly2 TUDOR
DOMAIN-CONTAINING
PROTEIN 7
(Mus
musculus) 		3 / 3 ILE A 422
ILE A 414
THR A 410
 None
 0.54A 1rg7A-2ly2A:
undetectable		 1rg7A-2ly2A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2ly2 TUDOR
DOMAIN-CONTAINING
PROTEIN 7
(Mus
musculus) 		4 / 7 VAL A 295
HIS A  -1
LEU A 291
ILE A 305
 None
 0.83A 3avpA-2ly2A:
undetectable		 3avpA-2ly2A:
21.25