SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_0
(PROTEIN (METHIONINE
REPRESSOR))		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 9 ARG A  84
LEU A  17
GLU A  18
ALA A  19
LEU A  21
 None
 1.33A 1mj2A-2lz1A:
undetectable		 1mj2A-2lz1A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_0
(PROTEIN (METHIONINE
REPRESSOR))		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 9 ARG A  84
LEU A  17
GLU A  18
ALA A  19
LEU A  21
 None
 1.30A 1mj2C-2lz1A:
undetectable		 1mj2C-2lz1A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		3 / 3 ARG A  23
ARG A  27
ARG A  71
 None
 0.96A 2jb7A-2lz1A:
undetectable
2jb7B-2lz1A:
undetectable
2jb7C-2lz1A:
undetectable		 2jb7A-2lz1A:
20.62
2jb7B-2lz1A:
20.62
2jb7C-2lz1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		3 / 3 ARG A  27
ARG A  71
ARG A  23
 None
 1.00A 2jb7A-2lz1A:
undetectable
2jb7B-2lz1A:
undetectable
2jb7C-2lz1A:
undetectable		 2jb7A-2lz1A:
20.62
2jb7B-2lz1A:
20.62
2jb7C-2lz1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		3 / 3 ARG A  71
ARG A  23
ARG A  27
 None
 1.03A 2jb7A-2lz1A:
undetectable
2jb7B-2lz1A:
undetectable
2jb7C-2lz1A:
undetectable		 2jb7A-2lz1A:
20.62
2jb7B-2lz1A:
20.62
2jb7C-2lz1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.10A 3k37A-2lz1A:
undetectable		 3k37A-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.11A 3k37B-2lz1A:
undetectable		 3k37B-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.18A 3k39A-2lz1A:
undetectable		 3k39A-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.18A 3k39B-2lz1A:
undetectable		 3k39B-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.19A 3k39C-2lz1A:
undetectable		 3k39C-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.17A 3k39E-2lz1A:
undetectable		 3k39E-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.17A 3k39F-2lz1A:
undetectable		 3k39F-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.17A 3k39G-2lz1A:
undetectable		 3k39G-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.18A 3k39H-2lz1A:
undetectable		 3k39H-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.18A 3k39I-2lz1A:
undetectable		 3k39I-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.17A 3k39J-2lz1A:
undetectable		 3k39J-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.17A 3k39K-2lz1A:
undetectable		 3k39K-2lz1A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 2lz1 NUCLEAR FACTOR
ERYTHROID 2-RELATED
FACTOR 2
(Homo
sapiens) 		5 / 12 ARG A  16
GLU A  18
LEU A  17
ARG A  84
ALA A  28
 None
 1.18A 3k39L-2lz1A:
undetectable		 3k39L-2lz1A:
16.49