SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2lzj UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Mus
musculus) 		5 / 12 THR A 244
VAL A 221
PHE A 250
VAL A 248
CYH A 234
 None
 1.27A 3u9fB-2lzjA:
undetectable
3u9fC-2lzjA:
undetectable		 3u9fB-2lzjA:
16.91
3u9fC-2lzjA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2lzj UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Mus
musculus) 		5 / 12 THR A 244
VAL A 221
PHE A 250
VAL A 248
CYH A 234
 None
 1.31A 3u9fH-2lzjA:
undetectable
3u9fI-2lzjA:
undetectable		 3u9fH-2lzjA:
16.91
3u9fI-2lzjA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2lzj UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Mus
musculus) 		5 / 12 THR A 244
VAL A 221
PHE A 250
VAL A 248
CYH A 234
 None
 1.27A 3u9fJ-2lzjA:
undetectable
3u9fK-2lzjA:
undetectable		 3u9fJ-2lzjA:
16.91
3u9fK-2lzjA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2lzj UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Mus
musculus) 		5 / 12 CYH A 234
THR A 244
VAL A 221
PHE A 250
VAL A 248
 None
 1.25A 3u9fP-2lzjA:
undetectable
3u9fS-2lzjA:
undetectable		 3u9fP-2lzjA:
16.91
3u9fS-2lzjA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 2lzj UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Mus
musculus) 		5 / 12 MET A 265
ILE A 277
PHE A 250
LEU A 270
THR A 274
 None
 1.29A 5tiwB-2lzjA:
undetectable		 5tiwB-2lzjA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 2lzj UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Mus
musculus) 		5 / 12 MET A 265
SER A 251
GLU A 252
VAL A 221
CYH A 234
 None
 1.19A 5vlmH-2lzjA:
undetectable		 5vlmH-2lzjA:
18.75