SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lzn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 2lzn DNA PRIMASE
(Staphylococcus
aureus) 		3 / 3 ARG A 579
GLU A 580
GLN A 595
 None
 1.05A 2p16A-2lznA:
undetectable		 2p16A-2lznA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2lzn DNA PRIMASE
(Staphylococcus
aureus) 		3 / 3 ASN A 501
GLU A 473
ARG A 474
 None
 0.75A 3wxoA-2lznA:
undetectable		 3wxoA-2lznA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2lzn DNA PRIMASE
(Staphylococcus
aureus) 		4 / 7 GLN A 568
GLY A 567
VAL A 560
SER A 573
 None
 0.98A 6hu9S-2lznA:
undetectable
6hu9q-2lznA:
1.4		 6hu9S-2lznA:
22.38
6hu9q-2lznA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 2lzn DNA PRIMASE
(Staphylococcus
aureus) 		4 / 7 GLN A 568
GLY A 567
VAL A 562
SER A 573
 None
 1.03A 6hu9S-2lznA:
undetectable
6hu9q-2lznA:
1.4		 6hu9S-2lznA:
22.38
6hu9q-2lznA:
16.00