SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2lzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 2lzu LIM
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		3 / 3 CYH A  43
CYH A  67
HIS A  64
 ZN  A 201 (-2.2A)
ZN  A 201 (-2.2A)
ZN  A 201 (-3.0A)
 0.61A 2iwkA-2lzuA:
undetectable		 2iwkA-2lzuA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 2lzu LIM
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		3 / 3 CYH A  43
CYH A  67
HIS A  64
 ZN  A 201 (-2.2A)
ZN  A 201 (-2.2A)
ZN  A 201 (-3.0A)
 0.60A 2iwkB-2lzuA:
undetectable		 2iwkB-2lzuA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 2lzu LIM
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 8 TYR A 105
GLU A 107
GLN A  96
CYH A  91
 None
None
None
ZN  A 202 (-2.3A)
 1.20A 3b9lA-2lzuA:
undetectable		 3b9lA-2lzuA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2lzu LIM
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		3 / 3 CYH A  43
CYH A  67
HIS A  64
 ZN  A 201 (-2.2A)
ZN  A 201 (-2.2A)
ZN  A 201 (-3.0A)
 0.53A 3dtuB-2lzuA:
undetectable		 3dtuB-2lzuA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2lzu LIM
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		3 / 3 CYH A  43
CYH A  67
HIS A  64
 ZN  A 201 (-2.2A)
ZN  A 201 (-2.2A)
ZN  A 201 (-3.0A)
 0.52A 3dtuD-2lzuA:
undetectable		 3dtuD-2lzuA:
13.64