SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2m0g SPLICING FACTOR 1
SPLICING FACTOR U2AF
65 KDA SUBUNIT
(Homo
sapiens;
Homo
sapiens) 		3 / 3 GLY A  71
THR A  26
ASN B 456
 None
 0.67A 3v4tD-2m0gA:
undetectable		 3v4tD-2m0gA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 2m0g SPLICING FACTOR U2AF
65 KDA SUBUNIT
(Homo
sapiens) 		3 / 3 LEU B 380
MET B 446
ASP B 441
 None
 0.92A 3v5wA-2m0gB:
undetectable		 3v5wA-2m0gB:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2m0g SPLICING FACTOR U2AF
65 KDA SUBUNIT
(Homo
sapiens) 		4 / 7 GLU B 393
TYR B 395
GLU B 396
ARG B 419
 None
 1.25A 4r87J-2m0gB:
undetectable
4r87L-2m0gB:
undetectable		 4r87J-2m0gB:
23.31
4r87L-2m0gB:
23.31