SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.90A 1t3rA-2m1iA:
undetectable		 1t3rA-2m1iA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.93A 1t7iA-2m1iA:
undetectable		 1t7iA-2m1iA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 11 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.89A 1t7jA-2m1iA:
undetectable		 1t7jA-2m1iA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.89A 2idwB-2m1iA:
undetectable		 2idwB-2m1iA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 12 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.91A 2nnkB-2m1iA:
undetectable		 2nnkB-2m1iA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.93A 3ektA-2m1iA:
undetectable		 3ektA-2m1iA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.98A 3gguB-2m1iA:
undetectable		 3gguB-2m1iA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.95A 3oxvA-2m1iA:
undetectable		 3oxvA-2m1iA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.94A 3oxwC-2m1iA:
undetectable		 3oxwC-2m1iA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.91A 3oy4B-2m1iA:
undetectable		 3oy4B-2m1iA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.91A 3u7sA-2m1iA:
undetectable		 3u7sA-2m1iA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.91A 4dqbB-2m1iA:
undetectable		 4dqbB-2m1iA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.92A 4dqcB-2m1iA:
undetectable		 4dqcB-2m1iA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.88A 4dqeB-2m1iA:
undetectable		 4dqeB-2m1iA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.90A 4dqhB-2m1iA:
undetectable		 4dqhB-2m1iA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.93A 4njtB-2m1iA:
undetectable		 4njtB-2m1iA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 9 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.93A 4q1wA-2m1iA:
undetectable		 4q1wA-2m1iA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 11 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.90A 4q1xA-2m1iA:
undetectable		 4q1xA-2m1iA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 2m1i PARVULIN-LIKE
PEPTIDYL-PROLYL
ISOMERASE
(Cenarchaeum
symbiosum) 		5 / 10 LEU A  16
ASP A  46
GLY A  48
ASP A  53
GLY A  57
 None
 0.91A 4q1yA-2m1iA:
undetectable		 4q1yA-2m1iA:
22.33