SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 2m1x TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 LEU A 533
LEU A 416
THR A 426
ALA A 450
ILE A 453
 None
 0.88A 4o2bD-2m1xA:
2.5		 4o2bD-2m1xA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2m1x TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 LEU A 533
LEU A 416
THR A 426
ALA A 450
ILE A 453
 None
 0.93A 4x1iD-2m1xA:
undetectable		 4x1iD-2m1xA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2m1x TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 LEU A 533
LEU A 416
THR A 426
ALA A 450
ILE A 453
 None
 0.92A 4x1yD-2m1xA:
undetectable		 4x1yD-2m1xA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2m1x TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 LEU A 533
LEU A 416
THR A 426
ALA A 450
ILE A 453
 None
 0.96A 4x20B-2m1xA:
undetectable		 4x20B-2m1xA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 2m1x TIR
DOMAIN-CONTAINING
ADAPTER MOLECULE 1
(Homo
sapiens) 		5 / 12 LEU A 533
LEU A 416
THR A 426
ALA A 450
ILE A 453
 None
 0.95A 5xiwB-2m1xA:
undetectable		 5xiwB-2m1xA:
16.37