SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		4 / 7 SER A  83
ASP A 122
SER A 123
SER A  79
 None
 1.08A 2cmlA-2m26A:
undetectable		 2cmlA-2m26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		4 / 8 SER A  83
ASP A 122
SER A 123
SER A  79
 None
 1.01A 2cmlB-2m26A:
undetectable		 2cmlB-2m26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		4 / 8 SER A  83
ASP A 122
SER A 123
SER A  79
 None
 1.05A 2cmlC-2m26A:
undetectable		 2cmlC-2m26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		4 / 8 SER A  83
ASP A 122
SER A 123
SER A  79
 None
 0.97A 2cmlD-2m26A:
undetectable		 2cmlD-2m26A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		4 / 7 GLU A  53
ALA A 110
GLY A 108
TYR A 107
 None
 1.09A 5uxdA-2m26A:
undetectable		 5uxdA-2m26A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		4 / 6 LEU A  24
VAL A  77
LEU A  82
VAL A  67
 None
 0.93A 5x7zA-2m26A:
undetectable		 5x7zA-2m26A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2m26 HCF C-TERMINAL CHAIN
1
(Mus
musculus) 		5 / 10 TRP A  26
ILE A  15
ILE A  36
ALA A 101
ALA A 110
 None
 1.50A 5zjiB-2m26A:
undetectable		 5zjiB-2m26A:
20.45