SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 2m38 ANKYRIN REPEAT AND
STERILE ALPHA MOTIF
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens) 		5 / 12 PHE A 125
PHE A  75
ILE A  92
ALA A  95
ALA A 130
 None
 1.15A 2j0dA-2m38A:
undetectable		 2j0dA-2m38A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 2m38 ANKYRIN REPEAT AND
STERILE ALPHA MOTIF
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens) 		4 / 7 THR A 136
GLY A 138
ALA A 140
ILE A  89
 None
 0.87A 4txnA-2m38A:
undetectable		 4txnA-2m38A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 2m38 ANKYRIN REPEAT AND
STERILE ALPHA MOTIF
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens) 		4 / 7 THR A 136
GLY A 138
ALA A 140
ILE A  89
 None
 0.85A 4txnB-2m38A:
undetectable		 4txnB-2m38A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 2m38 ANKYRIN REPEAT AND
STERILE ALPHA MOTIF
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens) 		4 / 7 THR A 136
GLY A 138
ALA A 140
ILE A  89
 None
 0.88A 4txnC-2m38A:
undetectable		 4txnC-2m38A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 2m38 ANKYRIN REPEAT AND
STERILE ALPHA MOTIF
DOMAIN-CONTAINING
PROTEIN 1B
(Homo
sapiens) 		4 / 7 THR A 136
GLY A 138
ALA A 140
ILE A  89
 None
 0.85A 4txnD-2m38A:
undetectable		 4txnD-2m38A:
20.83