SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NV4_A_ACTA148_0 (UPF0066 PROTEIN AF_0241)	2m45	MINICHROMOSOME MAINTENANCE PROTEIN MCM (Sulfolobus solfataricus)	3 / 3	VAL A 645 GLU A 677 GLU A 681	None	0.76A	2nv4A-2m45A: undetectable	2nv4A-2m45A: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J24_A_ESTA600_1 (ESTROGEN RECEPTOR BETA)	2m45	MINICHROMOSOME MAINTENANCE PROTEIN MCM (Sulfolobus solfataricus)	5 / 12	MET A 669 LEU A 666 LEU A 649 ILE A 633 ILE A 632	None	1.16A	4j24A-2m45A: undetectable	4j24A-2m45A: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_D_LOCD502_1 (TUBULIN BETA CHAIN)	2m45	MINICHROMOSOME MAINTENANCE PROTEIN MCM (Sulfolobus solfataricus)	5 / 12	LEU A 649 LYS A 664 LEU A 666 MET A 669 ILE A 633	None	1.06A	4x1iD-2m45A: undetectable	4x1iD-2m45A: 15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_D_LOCD502_1 (TUBULIN BETA CHAIN)	2m45	MINICHROMOSOME MAINTENANCE PROTEIN MCM (Sulfolobus solfataricus)	5 / 12	LYS A 664 LEU A 666 MET A 669 ALA A 652 ILE A 633	None	1.12A	4x1iD-2m45A: undetectable	4x1iD-2m45A: 15.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2NV4_A_ACTA148_0","UPF0066 PROTEIN AF_0241","2m45","MINICHROMOSOME MAINTENANCE PROTEIN MCM","Sulfolobus solfataricus",3,"VAL A 645;GLU A 677;GLU A 681","None","0.76A","2nv4A-2m45A:undetectable","2nv4A-2m45A:18.90"],["4J24_A_ESTA600_1","ESTROGEN RECEPTOR BETA","2m45","MINICHROMOSOME MAINTENANCE PROTEIN MCM","Sulfolobus solfataricus",5,"MET A 669;LEU A 666;LEU A 649;ILE A 633;ILE A 632","None","1.16A","4j24A-2m45A:undetectable","4j24A-2m45A:17.86"],["4X1I_D_LOCD502_1","TUBULIN BETA CHAIN","2m45","MINICHROMOSOME MAINTENANCE PROTEIN MCM","Sulfolobus solfataricus",5,"LEU A 649;LYS A 664;LEU A 666;MET A 669;ILE A 633","None","1.06A","4x1iD-2m45A:undetectable","4x1iD-2m45A:15.36"],["4X1I_D_LOCD502_1","TUBULIN BETA CHAIN","2m45","MINICHROMOSOME MAINTENANCE PROTEIN MCM","Sulfolobus solfataricus",5,"LYS A 664;LEU A 666;MET A 669;ALA A 652;ILE A 633","None","1.12A","4x1iD-2m45A:undetectable","4x1iD-2m45A:15.36"]]