SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
3 / 3 ARG A 133
VAL A  84
TRP A  91
None
1.10A 1qw6A-2m47A:
undetectable
1qw6A-2m47A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
3 / 3 ARG A 133
VAL A  84
TRP A  91
None
1.13A 1qwcA-2m47A:
undetectable
1qwcA-2m47A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
3 / 3 ARG A 133
VAL A  84
TRP A  91
None
1.08A 1vagA-2m47A:
undetectable
1vagA-2m47A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
3 / 3 ARG A 133
VAL A  84
TRP A  91
None
1.03A 1zviA-2m47A:
undetectable
1zviA-2m47A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
4 / 5 GLU A 143
PRO A 142
ILE A 141
GLY A 140
None
1.20A 2qeuA-2m47A:
undetectable
2qeuC-2m47A:
undetectable
2qeuA-2m47A:
20.83
2qeuC-2m47A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
3 / 3 GLU A 153
HIS A 162
HIS A 163
None
0.81A 3co4A-2m47A:
undetectable
3co4A-2m47A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
3 / 3 ARG A 133
VAL A  84
TRP A  91
None
1.11A 5fvoA-2m47A:
undetectable
5fvoA-2m47A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)
2m47 UNCHARACTERIZED
PROTEIN CGL2373

(Corynebacterium
glutamicum)
4 / 8 GLY A  51
HIS A  53
GLY A  87
SER A  83
None
0.71A 6hu9H-2m47A:
undetectable
6hu9e-2m47A:
undetectable
6hu9H-2m47A:
19.25
6hu9e-2m47A:
17.16