SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q7I_A_TESA205_1 (ANDROGEN RECEPTOR)	2m5j	HASR PROTEIN (Serratia marcescens)	5 / 12	LEU A 63 ASN A 111 GLN A 61 MET A 57 MET A 27	None	1.33A	2q7iA-2m5jA: undetectable	2q7iA-2m5jA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_A_SAMA401_0 (METHYLTRANSFERASE NSUN4)	2m5j	HASR PROTEIN (Serratia marcescens)	6 / 12	GLY A 95 ASN A 110 LEU A 87 GLY A 109 ASP A 100 LEU A 105	None	1.25A	4fp9A-2m5jA: undetectable	4fp9A-2m5jA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_C_SAMC401_0 (METHYLTRANSFERASE NSUN4)	2m5j	HASR PROTEIN (Serratia marcescens)	6 / 12	GLY A 95 ASN A 110 LEU A 87 GLY A 109 ASP A 100 LEU A 105	None	1.25A	4fp9C-2m5jA: undetectable	4fp9C-2m5jA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZDZ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2m5j	HASR PROTEIN (Serratia marcescens)	4 / 7	PHE A 16 PHE A 30 GLY A 62 LEU A 76	None	0.92A	4zdzA-2m5jA: undetectable	4zdzA-2m5jA: 11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M24_A_9CRA501_1 (RETINOIC ACID RECEPTOR GAMMA)	2m5j	HASR PROTEIN (Serratia marcescens)	5 / 12	ALA A 26 MET A 48 GLY A 68 LEU A 63 ILE A 18	None	1.08A	5m24A-2m5jA: undetectable	5m24A-2m5jA: 18.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Q7I_A_TESA205_1","ANDROGEN RECEPTOR","2m5j","HASR PROTEIN","Serratia marcescens",5,"LEU A  63;ASN A 111;GLN A  61;MET A  57;MET A  27","None","1.33A","2q7iA-2m5jA:undetectable","2q7iA-2m5jA:14.96"],["4FP9_A_SAMA401_0","METHYLTRANSFERASE NSUN4","2m5j","HASR PROTEIN","Serratia marcescens",6,"GLY A  95;ASN A 110;LEU A  87;GLY A 109;ASP A 100;LEU A 105","None","1.25A","4fp9A-2m5jA:undetectable","4fp9A-2m5jA:19.06"],["4FP9_C_SAMC401_0","METHYLTRANSFERASE NSUN4","2m5j","HASR PROTEIN","Serratia marcescens",6,"GLY A  95;ASN A 110;LEU A  87;GLY A 109;ASP A 100;LEU A 105","None","1.25A","4fp9C-2m5jA:undetectable","4fp9C-2m5jA:19.06"],["4ZDZ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","2m5j","HASR PROTEIN","Serratia marcescens",4,"PHE A  16;PHE A  30;GLY A  62;LEU A  76","None","0.92A","4zdzA-2m5jA:undetectable","4zdzA-2m5jA:11.78"],["5M24_A_9CRA501_1","RETINOIC ACID RECEPTOR GAMMA","2m5j","HASR PROTEIN","Serratia marcescens",5,"ALA A  26;MET A  48;GLY A  68;LEU A  63;ILE A  18","None","1.08A","5m24A-2m5jA:undetectable","5m24A-2m5jA:18.40"]]