SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2m5w LUPUS LA PROTEIN
(Dictyostelium
discoideum) 		4 / 5 LEU A  60
GLN A   8
THR A   5
GLU A  63
 None
 1.48A 3n58C-2m5wA:
undetectable		 3n58C-2m5wA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 2m5w LUPUS LA PROTEIN
(Dictyostelium
discoideum) 		3 / 3 ARG A  70
ARG A  82
ILE A  90
 None
 0.88A 4b7qA-2m5wA:
undetectable		 4b7qA-2m5wA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2m5w LUPUS LA PROTEIN
(Dictyostelium
discoideum) 		3 / 3 ASP A  25
LEU A  28
PHE A  27
 None
 0.62A 4pthA-2m5wA:
undetectable		 4pthA-2m5wA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2m5w LUPUS LA PROTEIN
(Dictyostelium
discoideum) 		5 / 12 GLN A  59
VAL A  80
SER A  55
LEU A  60
ILE A   9
 None
 1.23A 5uahC-2m5wA:
undetectable		 5uahC-2m5wA:
5.22