SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  98
GLY A  95
VAL A  37
ILE A 117
VAL A 116
 None
 1.20A 1phgA-2m5yA:
undetectable		 1phgA-2m5yA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		4 / 6 VAL A  94
THR A  97
LEU A  56
ARG A  51
 None
 0.98A 1s8fB-2m5yA:
undetectable		 1s8fB-2m5yA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		4 / 5 VAL A  39
VAL A  66
THR A  77
THR A  64
 None
 1.19A 3bjwC-2m5yA:
undetectable		 3bjwC-2m5yA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		4 / 5 VAL A  39
VAL A  66
THR A  77
THR A  64
 None
 1.24A 3bjwD-2m5yA:
undetectable		 3bjwD-2m5yA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 11 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.75A 4qvlK-2m5yA:
undetectable
4qvlL-2m5yA:
undetectable		 4qvlK-2m5yA:
19.34
4qvlL-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 11 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.74A 4qvlY-2m5yA:
undetectable
4qvlZ-2m5yA:
undetectable		 4qvlY-2m5yA:
19.34
4qvlZ-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 9 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.74A 4qvmK-2m5yA:
undetectable
4qvmL-2m5yA:
undetectable		 4qvmK-2m5yA:
19.34
4qvmL-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 10 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.73A 4qvmY-2m5yA:
undetectable
4qvmZ-2m5yA:
undetectable		 4qvmY-2m5yA:
19.34
4qvmZ-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 10 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.73A 4qvpK-2m5yA:
undetectable
4qvpL-2m5yA:
undetectable		 4qvpK-2m5yA:
20.28
4qvpL-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 10 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.73A 4qvpY-2m5yA:
undetectable
4qvpZ-2m5yA:
undetectable		 4qvpY-2m5yA:
20.28
4qvpZ-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 11 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.73A 4qw1K-2m5yA:
undetectable
4qw1L-2m5yA:
undetectable		 4qw1K-2m5yA:
18.87
4qw1L-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 10 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.72A 4qw1Y-2m5yA:
undetectable
4qw1Z-2m5yA:
undetectable		 4qw1Y-2m5yA:
18.87
4qw1Z-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 10 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.75A 4qw3K-2m5yA:
undetectable
4qw3L-2m5yA:
undetectable		 4qw3K-2m5yA:
19.34
4qw3L-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 10 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.74A 4qw3Y-2m5yA:
undetectable
4qw3Z-2m5yA:
undetectable		 4qw3Y-2m5yA:
19.34
4qw3Z-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 11 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.76A 5bxnK-2m5yA:
undetectable
5bxnL-2m5yA:
undetectable		 5bxnK-2m5yA:
19.34
5bxnL-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 11 THR A  64
THR A  90
ALA A  93
GLY A  60
ALA A  59
 None
 0.75A 5bxnY-2m5yA:
undetectable
5bxnZ-2m5yA:
undetectable		 5bxnY-2m5yA:
19.34
5bxnZ-2m5yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 118
GLU A 108
ALA A  91
VAL A  94
GLY A  86
 None
 1.02A 5igjA-2m5yA:
undetectable		 5igjA-2m5yA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2m5y PUTATIVE TUBERCULIN
RELATED PEPTIDE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 118
GLU A 108
ALA A  91
VAL A  94
GLY A  86
 None
 0.99A 5igtA-2m5yA:
undetectable		 5igtA-2m5yA:
17.28