SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m6k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.90A 1v55A-2m6kA:
undetectable
1v55J-2m6kA:
undetectable		 1v55A-2m6kA:
18.83
1v55J-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 8 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.90A 1v55N-2m6kA:
undetectable
1v55W-2m6kA:
undetectable		 1v55N-2m6kA:
18.83
1v55W-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 6 LEU A 115
ALA A 137
HIS A  37
ASP A  32
 None
 1.32A 2dpzA-2m6kA:
undetectable		 2dpzA-2m6kA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 8 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.88A 2einA-2m6kA:
undetectable
2einJ-2m6kA:
undetectable		 2einA-2m6kA:
18.83
2einJ-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		3 / 3 SER A  41
ARG A  28
GLN A  42
 None
 0.92A 2xnrA-2m6kA:
undetectable		 2xnrA-2m6kA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 8 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.92A 3abmN-2m6kA:
undetectable
3abmW-2m6kA:
undetectable		 3abmN-2m6kA:
18.83
3abmW-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		5 / 10 ALA A 251
GLY A 253
LEU A 259
ASN A 249
ILE A 194
 None
 1.15A 3wdmB-2m6kA:
2.2		 3wdmB-2m6kA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 5 GLY A  68
THR A  54
ILE A  65
VAL A  64
 None
 0.73A 3wriA-2m6kA:
undetectable		 3wriA-2m6kA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 5 GLY A  68
THR A  54
ILE A  65
VAL A  64
 None
 0.72A 3wriB-2m6kA:
undetectable		 3wriB-2m6kA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 ASP A  61
GLY A 161
THR A 160
ILE A 159
 None
 0.95A 4acaC-2m6kA:
2.7		 4acaC-2m6kA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		3 / 3 PHE A 173
THR A 296
LEU A 219
 None
 0.63A 4qztA-2m6kA:
undetectable		 4qztA-2m6kA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.96A 5b1aA-2m6kA:
undetectable
5b1aJ-2m6kA:
undetectable		 5b1aA-2m6kA:
18.83
5b1aJ-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 4 LEU A 245
ILE A 243
PRO A 227
LEU A 254
 None
 1.22A 5eb3A-2m6kA:
undetectable		 5eb3A-2m6kA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 GLY A  68
THR A  54
ILE A  65
VAL A  64
 None
 0.74A 5ik1A-2m6kA:
undetectable		 5ik1A-2m6kA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 6 GLY A 247
GLU A 248
TYR A 196
ILE A 194
 None
 0.92A 5kmfA-2m6kA:
undetectable
5kmfC-2m6kA:
undetectable		 5kmfA-2m6kA:
21.69
5kmfC-2m6kA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		3 / 3 SER A 210
ALA A 211
THR A  52
 None
 0.74A 5n0xB-2m6kA:
undetectable		 5n0xB-2m6kA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.96A 5xdxA-2m6kA:
undetectable
5xdxJ-2m6kA:
undetectable		 5xdxA-2m6kA:
18.83
5xdxJ-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.84A 6nmfA-2m6kA:
0.0
6nmfJ-2m6kA:
undetectable		 6nmfA-2m6kA:
18.83
6nmfJ-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 7 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.77A 6nmpA-2m6kA:
undetectable
6nmpJ-2m6kA:
undetectable		 6nmpA-2m6kA:
18.83
6nmpJ-2m6kA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m6k FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN
(Escherichia
coli) 		4 / 5 ILE A 142
LEU A 117
THR A  38
LEU A  39
 None
 0.74A 6nmpN-2m6kA:
undetectable
6nmpW-2m6kA:
undetectable		 6nmpN-2m6kA:
18.83
6nmpW-2m6kA:
10.58